Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids. In most of these diseases, researchers have identified the proteins that aggregate, ...

Purdue researchers have created molecular compounds to inhibit protein aggregation linked with Alzheimer’s disease, Parkinson’s disease and Type 2 diabetes WEST LAFAYETTE, Ind. — Purdue University ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases. These disorders ...

Raghu R. Chivukula, MD, Ph.D., a physician-investigator in the Departments of Medicine & Surgery and the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, is ...

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases. To overcome these limitations, scientists developed the real-time quaking-induced ...

Intracellular proteins that condense into droplets via liquid-liquid phase separation (LLPS) have been suspected of favoring the formation of amyloid fibrils, and thereby causing neurodegenerative ...

A team of researchers from Mass General Brigham led by Raghu Chivukla, MD, PhD released a new study linking protein aggregation to altered RNA processing in genetic forms of neurodegeneration.

Dr. Tiwari is a broadly trained protein chemist and cell biologist. His research is in the area of ‘protein aggregation diseases' with special emphasis on age related neurodegenerative disorders such ...

A technique that can detect and measure small protein aggregates, which are hallmarks of numerous neurodegenerative diseases, has been developed. Protein aggregation – when proteins misfold and clump ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson’s disease, shows study. Rather, the formation of protein into liquid droplets ...