If the cell cycle were like a particular score played by a molecular orchestra, E2F7 was a new conductor, guiding the same instruments in that orchestra to play a new tune, the multiciliation cycle.

The cell cycle contains 4 stages; Gap 1 (G1) phase, synthesis (S) phase, gap 2 (G2) phase and mitosis (M) phase. For most human cells, a single cell cycle takes approximately 24 hours.

They found that one factor, called E2F7, was expressed at higher levels in the multiciliation cycle. When the team knocked out E2F7 in mice, they found that the multiciliated cells in these mice had ...

Cell cycle speed is key to making aging cells young again Date: January 30, 2014 Source: Yale University Summary: Researchers identified a major obstacle to converting cells back to their youthful ...

The cell cycle also serves to protect the cell from DNA damage. Thus, cell cycle arrest, in fact, represents a survival mechanism that provides the tumor cell the opportunity to repair its own damaged ...

To understand the dynamics of cell-cycle status in tumors, Florian’s team used two new reporters: one to visualize G1 and the other to see G2, S, and M phases. “Because [FUCCI4] uses fluorescent ...

These patterns of macromolecule production timing during the cell cycle are relevant contributions, said Nicolas Buchler, a biophysicist at the North Carolina State University who was not involved in ...

Role of cell cycle progression on analyzing telomerase in cancer cells based on aggregation-induced emission luminogens Natl Sci Rev,2021, doi: 10.1093/nsr/nwaa306 ...

Discovery within human cell cycle process to bring new understanding of cellular diseases Date: July 27, 2021 Source: University of Kent Summary: New research has uncovered an essential mechanism ...

3'RNA sequencing was performed in 1,733 patients from the PETACC-8 trial and 1,248 patients from the IDEA-France trial. Four transcriptomic signatures were analyzed: T-cell and macrophage M2 ...