Christina Applegate, who revealed her multiple sclerosis diagnosis in 2021, says she's been hospitalized 'upwards of 30 times' from vomiting, diarrhea, and pain she believes are tied to the condition.

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, I’ve been in the hospital upwards of 30 times from throwing up and diarrhea and pain,” Applegate, 53, revealed on Tuesday’s episode of her and Jamie Lynn Sigler’s “MeSsy” podcast.

Christina Applegate shared that she thinks her gastrointestinal symptoms are related to multiple sclerosis, explaining, "I get all the pain" from bowel movements.