There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will fit into a cell’s nucleus, while the crucial parts of it remain accessible ...

Movie 1: Movement of single nucleosomes in living human cells. The movie shows nucleosome fluctuations in euchromatin (left), where gene expression is active, and in heterochromatin (right), where ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...