Studies of the genomic DNA compaction in the cell nucleus and dynamic reorganization during physiologic processes or disease development in live cell environment are exceedingly challenging. This ...

Using magnets and video microscopy to measure the length of individual DNA molecules under experimental conditions, researchers have demonstrated that Condensin, a complex of proteins widely conserved ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new ...

Mitotic chromosomes are pivotal for the inheritance of genetic material. Now, it is already known that chromosomes vary in dimensions among organisms. But what governs mitotic chromosomal size and ...

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA ...

A research team have discovered a mechanism of flowering plant sperm compaction and gathered clues as to why it is required. Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell ...

KANAZAWA, Japan, April 3, 2025 /PRNewswire/ -- Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA ...

Mitochondrial DNA (mtDNA) exhibits a degree of resistance to mutagenesis under genotoxic stress, and this study on the mitochondrial Transcription Factor A (TFAM) presents valuable data concerning the ...

Founded in 2005, Complete Genomics was the first to make whole genome sequencing (WGS) services affordable. Now, the company provides complete solutions to sequencing labs with an installed base of ...

Small basic proteins present in most Archaea share a common ancestor with the eukaryotic core histones. We report the crystal structure of an archaeal histone-DNA complex. DNA wraps around an extended ...