When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...
Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...
Distant metastasis and recurrence remain major obstacles limiting the long-term efficacy of immunotherapy for solid tumors, particularly in highly aggressive cancers, such as malignant melanoma.
The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...
The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or ...
The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...
A new study shows human immune systems differ across populations, raising new questions for medicine and global drug research ...
Multicellular organisms are a mosaic of different cells, tissues, and systems, each with their own specific function and interactions with other cells within the organism and/or the larger environment ...
New Study Shows SIK1 Strengthens Antiviral Immunity to Limit EV-D68–Induced Asthma Exacerbations Asthma is a chronic ...
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