Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...

The Finnish population has provided investigators with a rare opportunity. Most Finns descend from a small, so-called founder population of individuals, and people have primarily reproduced with ...

Dear Readers: For most people, finding out that they have come into an inheritance is a positive experience. Not so when that inheritance is early onset familial Alzheimer's disease (eFAD). This type ...

The study focused on so-called coding genetic variants, i.e. variants that are known to change the protein product of the gene. The results of the study, published in Nature on January 18, 2023, ...

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen ...

The earliest studies of genetic inheritance were very straightforward - Gregor Mendel documented the passage of certain easily observable traits as they passed down through generations of pea plants.

The genotype of an organism is inherited from its parents through the process of reproduction. During sexual reproduction, each parent contributes half of the genetic material to the offspring, ...

I recently underwent genetic testing to see if I had any mutations that could be associated with an increased cancer risk. When I received my genetic testing kit in the mail, I quickly opened the ...