A new study has found an association between elevated levels of a protein, known as Miro1, in skeletal muscle and type 2 ...

Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...

Insulin resistance has emerged as a central pathophysiological mechanism underlying a broad spectrum of metabolic disorders, ...

Insulin receptor (IR) is a tyrosine kinase involved in vital cellular signaling processes related to glucose metabolism and cell growth. Detailed understanding of molecular mechanisms of IR signaling ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

The insulin receptor entrains tissue growth and metabolism to nutritional conditions. Complete loss of function in humans leads to extreme insulin resistance and infantile mortality, while loss of ...

Recent research published in the journal Diabetes sheds new light on the cellular mechanisms causing insulin resistance in type 2 diabetes, a disease affecting more than 1.2 million people in Quebec ...

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity. The insulin superfamily of hormones, ...

The FDA has expanded the indication of once-weekly basal insulin icodec-abae to include children and adolescents aged 10 years and older with type 2 diabetes.

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Scientists at the Research Center for Molecular Medicine of the Austrian Academy of Sciences have demonstrated that targeting the chromatin protein SMNDC1 will stimulate alpha cells to produce insulin ...

Insulin under normal circumstances exerts its antiatherogenic action in endothelial cells and VSMCs via the PI 3-kinase signaling pathway. Antiatherogenic aspects of insulin action include stimulation ...