Nature

The long noncoding RNA AC093895.1 promotes ovarian cancer formation and metastasis through a positive feedback network dependent on the transcription factor SOX4

Recurrence and metastasis are the main causes of death in ovarian cancer (OC). Long non-coding RNAs (lncRNAs) are considered as good prognostic models and potential therapeutic targets for cancer ...
Nature

The long non-coding RNA RSDR protects against acute kidney injury in mice by interacting with hnRNPK to regulate DHODH-mediated ferroptosis

The alternative text for this image may have been generated using AI. Fig. 2: RSDR Alleviates renal tubular epithelial cell injury in vivo and in vitro. The alternative text for this image may have ...
Medical Xpress

A long non-coding RNA, TERRA, is associated with human aging and Alzheimer's diseases

A research team from National Taiwan University, Academia Sinica, and National Taiwan University Hospital has uncovered a critical connection between a unique RNA molecule and human aging, including ...
Medical Xpress

Long non-coding RNA may be a promising therapeutic target for cancer

Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its ...
The Scientist

Postdoc Portrait: Kaushik Chanda Studies Circular RNA in Neurodegeneration

Scripps Research postdoctoral researcher Kaushik Chanda explores the mechanisms by which non-coding transcripts modulate neuronal function and structural integrity during learning and memory loss.