Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...

The strong allogeneic response to donor MHC molecules in transplantation and the weak response to tumor antigens represent two important and divergent but potentially interactive immune responses.

While it's known that major histocompatibility complex class I (MHC-I) plays a central role in orchestrating immune responses to cancer, less is known about the reactivity of peptides displayed by ...

Although elegant, this model was not verified. Hybrid resistance was mapped to several putative Hh loci located close to MHC class I genes, but no corresponding genes or antigens were ever found.