Mesenchymal stromal/stem cells (MSCs) form a heterogeneous population of multipotent progenitors that contribute to tissue regeneration and homeostasis. MSCs assess extracellular elasticity by probing ...

Bioengineers at the University of California, San Diego have proven that when it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them ...

Gastric cancer is the most common malignant gastrointestinal cancer and accounts for 25% of cancer deaths. Nuclear matrix, a filamentous protein framework for eukaryotic cellular chromatin, closely ...

Subcutaneous implantation of demineralized diaphyseal bone matrix in allogeneic rats results in the local induction of endochondral bone differentiation. We have explored the potential of three ...

This study evaluates whether rabbits are a suitable animal model to study post-natal vitreous differentiation and degeneration. The global vitreous matrix organization is similar in human and rabbit ...

Mechanical factors are as important as the chemical factors in regulating differentiation of adult stem cells. “We show, for the first time, that we can predict stem cell differentiation as early as ...

Bioengineers have demonstrated that the stiffness of the extracellular matrix used to culture stem cells really does matter. The research team also found that a protein binding the stem cell to the ...