South Carolina is bracing for another major winter storm this weekend, following last week’s heavy snow and ice.

When will the snow start in the Upstate area of South Carolina?

Up to 12 inches of snow is possible in some areas.

A major winter storm is expected to sweep across North Carolina this weekend, bringing a mix of snow, sleet and ice.

Preliminary snow totals in South Carolina, North Carolina and Georgia

Local reports said the pileup involved as many as 100 vehicles and it wasn't immediately known how many injuries there were. The collision occurred in the northbound lanes of the interstate near Kannapolis, North Carolina, where at least 14.5 inches of snow have fallen Saturday during Winter Storm Gianna.

Wondering about road conditions in South Carolina, the Upstate? How to find the latest conditions and view live DOT road cameras.

The entire state of South Carolina will be under an Extreme Cold Warning through Sunday morning after snow blanketed the area on Saturday.