Two proteins central to the pathology of Alzheimer's disease act as prions -- misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded ...

August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

Researchers this week say their work should upturn the conventional narrative of how Alzheimer’s disease happens. They argue the progression of Alzheimer’s is driven by a very specific form of two ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form ...

Kuru A virtually extinct form of human prion disease of the Fore linguistic group of Papua New Guinea transmitted via ritualistic endocannibalism. Mainly affected women and young children. Some ...

Prion diseases are rare and occur due to proteins in the brain that “misfold.” Another name for prion disease is transmissible spongiform encephalopathies (TSEs). There are many types of prion ...

A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since ...

"I believe this shows beyond a shadow of a doubt that amyloid beta and tau are both prions, and that Alzheimer's disease is a double-prion disorder in which these two rogue proteins together destroy ...