Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study. The findings advance ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

The innate immune protein C1q seems to have a thing for neurons. Already implicated in synaptic pruning by microglia, now it is reported to also slow down protein production in neurons of the aging ...

More than a century ago, the anatomist Santiago Ramón y Cajal unveiled his incredibly detailed drawings of neurons. From these, he posited that neurons were the main building blocks of the brain and ...