Spermatogenesis in mammals is crucial for male fertility. It starts after birth and continues throughout life, relying on spermatogonial stem cells (SSCs). SSCs can differentiate into early ...
In unirradiated testes large differences were found in the total number of spermatogonia among different monkeys, but the number of spermatogonia in the right and the left testes of the same monkey ...
In the present work, we show that the Fgf9 antimeiotic effect is mediated by activation of the Cripto-Nodal-Smad2/3 signaling in postnatal spermatogonia, and that this activation requires ...
For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend ...
ASHBi researchers now reveal the mechanisms driving epigenetic reprogramming and differentiation during human germ cell development, enabling the near-indefinite amplification of mitotic ...
It’s well established that older men are more likely to pass on a genetic disorder to their offspring, but we’re learning more about why this happens: As men age, their sperm mutates more frequently.
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