Response to Cyclophosphamide, Methotrexate, and Fluorouracil in Lymph Node–Positive Breast Cancer According to HER2 Overexpression and Other Tumor Biologic Variables PURPOSE: To identify predictors of ...

Neoadjuvant Capecitabine and Oxaliplatin Followed by Synchronous Chemoradiation and Total Mesorectal Excision in Magnetic Resonance Imaging–Defined Poor-Risk Rectal Cancer Adjuvant chemotherapy ...

The Breast International Group (BIG) 1-98 study evaluated adjuvant endocrine therapy in postmenopausal women who had hormone receptor-positive early-stage breast cancer. The study participants were ...

Scientists are reporting what they say is the best evidence yet that the drug Tamoxifen can prevent breast cancer. But some researchers say the drug — which is used primarily to treat women who've ...

Please provide your email address to receive an email when new articles are posted on . Patients with DCIS who received tamoxifen had a lower 15-year risk for ipsilateral breast cancer recurrence.

Tamoxifen reduces the rate of breast cancer recurrence by approximately a half. Tamoxifen is metabolized to more active metabolites by enzymes encoded by polymorphic genes, including cytochrome P450 ...

Endocrine therapy has long been a cornerstone for treating estrogen receptor-positive (ER+) breast cancer, which makes up about 75% of all breast cancer cases. Yet, a significant number of patients ...