Dystonia is a disorder of motor programmes controlling semiautomatic movements or postures, with clinical features such as sensory trick , which suggests sensorimotor mismatch as the basis. Dystonia ...

Objective To determine the diagnostic and prognostic performance of serum neurofilament light chain (NFL) in amyotrophic lateral sclerosis (ALS). Methods This single-centre, prospective, longitudinal ...

Better classification of headache disorders enables better headache research, understanding of headache, communication, and, ultimately, management of a set of disabling neurological disorders In the ...

OBJECTIVE Neuropsychiatric symptoms are common in Huntington's disease and have been considered its presenting manifestation. Research characterising these symptoms in Huntington's disease is variable ...

The diagnosis of post-encephalitic Parkinsonism is rarely entertained today. In this paper we discuss eight recent patients, six of whom presented in the last 20 years, that conform to the diagnosis ...

Background: Therapeutic outcome of Wilson’s disease (WD) significantly depends upon its early recognition. However, because of its rarity in community and protean manifestations, the diagnosis and ...

Objective To perform a systematic review of cases reported in the literature in which a peripheral trauma preceded the onset of a movement disorder (MD). Methods Two reviewers independently searched ...

The psychology and biology of a complex developmental condition Autism is diagnosed when a child or adult has abnormalities in a “triad” of behavioural domains: social development, communication, and ...

Introduction Post-stroke fatigue negatively influences short-term functional outcome in older stroke survivors. In young adults, in the midst of their active working and family life, this influence ...

Background and objective: Cryoglobulinaemic neuropathy (CN) is probably common, as it is usually related to HCV infection. The aim of this study was to delineate the clinical spectrum of CN in a large ...

Background Peripheral inflammation has long been hypothesized to contribute to Huntington’s disease (HD) pathophysiology. Increased peripheral inflammation has been implicated in ‘sickness behavior,’ ...

The clinical effects of botulinum toxin have been recognised since the end of the 19th century. It is the most potent neurotoxin known and it is produced by the gram negative anaerobic bacterium ...