iQue® Immune Cell-based kits for immunophenotyping and function iQue® SARS-CoV-2 (IgG, IgM, and IgA) kit for COVID-19 research iQue® Software Module for 21 CFR Part 11 ...

p53-mediated cell cycle arrest results demonstrate potential of ALRN-6924 to prevent chemotherapy-induced neutropenia, thrombocytopenia, and anemia, as well as chemotherapy-induced alopecia (hair ...

Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids (Cell Reports 2023) Published:12/26/2023 12/26/2023 • By Yao Rong , Alicia M. Darnell , Kiera M. Sapp , ...

Oncotarget published "NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells" which reported that peripheral T-cell lymphoma is characterized by ...

The cell cycle also serves to protect the cell from DNA damage. Thus, cell cycle arrest, in fact, represents a survival mechanism that provides the tumor cell the opportunity to repair its own damaged ...

On February 19, 2023, Mikhail V. Blagosklonny published a new review in Aging's Volume 15, Issue 4, entitled, “Cellular senescence: when growth stimulation meets cell cycle arrest.” ...

Using cell-based assays, patient-derived xenografts (PDX), and transgenic mouse models, we show that INX-315 (i) promotes retinoblastoma protein hypophosphorylation and therapy-induced senescence (TIS ...

Results: X003, WA, and X001 inhibited MDA-MB-231 cell viability (IC 50 =125, 500 and 1300nM respectively). IC 50 level of WA induced G2/M phase cell cycle arrest while 2.5μM also induced apoptosis at ...