By applying a second inhibitor (flavopiridol) that blocks the activity of Cdk–cyclin ... the cell cycle, so crucial to the long term viability of cells, is a systems-level property of the ...
Transcript processing provides an additional level of regulation for ... can progress from one phase of the cell cycle to the next, it must degrade the cyclin that characterizes that particular ...
WILMINGTON, DE — NiKang Therapeutics® Inc. has achieved a pivotal step in the development of its first-in-class CDK2 degrader, NKT3964, by completing the dosing of the first patient cohort in a ...