When you follow a 24-hour fast, once or twice a week, it triggers significant metabolic shifts in the body. Your body adapts to no calorie intake, primarily using stored energy sources. This affects ...

A detailed overview of the pathophysiology of diabetes mellitus, covering key mechanisms, disease progression, metabolic ...

How leptin signalling produces anti‑obesity effects is incompletely understood. Here, the authors demonstrate that FAK and PYK2 are required for STAT3 activation, normal leptin responses, and HDAC6 ...

Understand why routine lactate rechecks every 3–4 hours for days, prompting more fluids and vasopressors, can worsen outcomes ...

Glycosylation is a critical post-translational modification that plays a pivotal role in several biological processes, such as the immune response. Alterations in glycosylation can modulate the course ...

Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a key player in the pathogenesis of Diabetic Ulcers (DUs). Concurrently, Glucolipid Metabolic ...