A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

Type 1 dendritic cells are key to initiate and maintain anti-tumoral T-cell responses in diverse tumour tissues. Our lab focuses on tissue-specific properties of cDC1 in lung tumours, focusing on the ...

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review ...

A new study has revealed that ferulic acid, a natural compound found in various plant-based foods, can significantly inhibit the growth and migration of colon cancer cells at different stages of ...

Mushrooms found in the forests of Bankura and Birbhum in West Bengal could become a game-changer in cancer treatment.

The DREAM repressor complex regulates genes involved in the cell cycle and DNA repair, vital for maintaining genome stability. Although it mediates p53-driven repression through the canonical ...

stimulating p53 at frequencies that result in increased DNA repair gene expression and better maintenance of cell cycle arrest can aid in better recovery of cells in cases such as damage due to ...

When p53 accumulates in the nucleus, it leads to disrupted DNA repair processes, cell cycle arrest, and increased apoptosis. This mechanism is underscored by the antitumor effects in p53-dependent ...

Further analysis showed that although DHIE had opposite regulatory effects on different isoforms of p53 in different types of breast cancer cells, they eventually caused cell cycle arrest. In addition ...