Meeting a key secondary endpoint, more patients on obinutuzumab achieved a complete renal response with a prednisone taper to 7.5 mg/day or lower between weeks 64 and 76 (42.7% vs 30.9% ...

As a result, there is no evidence from controlled studies on the efficacy of different initial doses or drug tapering. The only controlled study suggests that initial prednisone doses ≤ 10 mg is ...

The data, which so far have been presented only in abstract form, suggest that budesonide is efficient in inducing stable remission, is superior compared with a standard prednisone-tapering ...

A phase 2 study evaluated the use of ruxolitinib plus standard GVHD prophylaxis in patients with myelofibrosis undergoing ...

Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that a detailed analysis of its phase III REGENCY trial of Gazyva®/Gazyvaro® (obinutuzumab) in people with active lupus nephritis (LN) was published ...

The gradual tapering was designed to avoid an abrupt discontinuation of prednisone which might favour prednisone. Visit 3 occurred 4–12 weeks after visit 2 (or was omitted for participants with a ...

long term clinical response and faster prednisone tapering compared to conventional immunosuppressive therapies, leading to its approval as a first line therapy in pemphigus. Other anti B-cell ...

Dr. Lu-Culligan: The patient completed the tapering prednisone course in 7 weeks, with resolution of the musculoskeletal pain and rash, along with normalization of the erythrocyte sedimentation ...

Prednisone is commonly prescribed, with an initial high-dose regimen of 1 mg/kg/day (up to 80 mg/day), followed by a gradual taper based on clinical response and biochemical markers such as ...

Gazyva/Gazyvaro (obinutuzumab) was found to significantly improve complete renal response in lupus nephritis patients, reinforcing its potential as an effective treatment option while also allowing ...

should be minimised to less than 7.5 mg/day (prednisone equivalent) and, when possible, withdrawn. Appropriate initiation of immunomodulatory agents (methotrexate, azathioprine, mycophenolate) can ...