Some signals help the tumor grow, while others help the immune system fight back. The same signal can thus mean different things in different cells. One example is the JAK-STAT pathway. It helps cells ...

A new diffusion MRI approach offers a glimpse of the anomalies of cellular architecture underlying basal ganglia degeneration in Huntington’s disease.

Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing ...

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Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein ...

ACC contains specialized neurons that sustain rich action-relevant information after action execution, enabling prolonged action monitoring, and supporting complex associative linking across events.

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

Integrating case counts with genomic sequences quantifies real-time transmission advantages of viral variants.

Chantreau M, Poux C, Lensink MF, Brysbaert G, Vekemans X, Castric V. 2019. Asymmetrical diversification of the receptor-ligand interaction controlling self-incompatibility in Arabidopsis. eLife ...

The authors present a solid study in the unique conditions of weightlessness providing evidence that movements carried out in 0g are underactuated. They further provide a thorough discussion based on ...

The spatial organization of chromatophore-muscle innervation by motoneurons enables the generation of chromatophore-shaped noise, virtual or composite chromatophores, and shape elements such as lines ...