Background Pancreatic ductal adenocarcinoma (PDAC) is largely refractory to immune checkpoint blockade, owing to its ...

We read with great interest the recent study by Lau et al , who reported distinct intrahepatic hepatitis B virus (HBV) ...

Background Endoscopic submucosal dissection (ESD) enables en bloc resection of early gastrointestinal cancers and provides ...

The trial by Yadav and colleagues concludes that proton pump inhibitors (PPIs) should be continued routinely after endoscopic ...

We read the global analysis of chronic kidney disease (CKD) in cirrhosis by Wong et al with great interest.1 Assembling 7040 ...

Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers due to its aggressive biology and ...

Tissue epithelia maintain their lineage identity under normal conditions but occasionally undergo ‘reprogramming’ into ...

Endoscopic submucosal dissection (ESD) enables en bloc resection for early gastrointestinal malignancies but is technically challenging. A novel, endoluminal robotic platform was developed to address ...

Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...

A systematic study of the distribution of Paneth cells in disease of the small and large intestine is described. In disease of the small intestine and appendix there is usually a fall in the number of ...

8 Women's and Children's Hospital, South Australia, Australia Objective The purpose of this study was the clinical and pathological characterisation of a new autosomal dominant gastric polyposis ...

Clinic for Internal Medicine I, University Hospital of Ulm, Ulm, Germany Background: CD147 (basigin, EMMPRIN) is a multifunctional, highly conserved glycoprotein enriched in pancreatic ductal ...