San Francisco is a 2.5-point favorite in the latest 49ers vs. Giants odds from SportsLine consensus, while the over/under for total points scored is 48.5. The 49ers are -151 money line favorites (risk ...

The New York Giants host the San Francisco 49ers at MetLife Stadium in East Rutherford, New Jersey, this Sunday at 1:00 p.m. EDT.

The 49ers (5-3) and the Giants (2-6) renew a storied rivalry Sunday at MetLife Stadium as each cope with the losses of big-time stars.

The 49ers traded for defensive lineman Keion White this week, but that doesn't mean they're done adding pass rushers.

The San Francisco 49ers are one of the most banged teams in the NFL right now, with a question mark at quarterback every week.

The San Francisco 49ers announce that Mac Jones will get another start at quarterback ahead of the Week 9 game vs. the New ...

San Francsico 49ers QB Brock Purdy (toe) is questionable for San Francisco's Week 9 game against the New York Giants on Sunday, coach Kyle Shanahan told reporters Friday, adding that he's "has got a ...

The 49ers just bolstered their defensive line group, but not in the way you might have thought that they would.

Smith was the first lineman the Cowboys took in the top-10 of the NFL Draft in the Jerry Jones era. He made the NFL’s ...

The San Francisco 49ers on Monday opened the practice window for second-year safety Malik Mustapha. Mustapha was participating in the individual portion of Monday's bonus practice for the 49ers ...

Former Nebraska running back Roger Craig is a candidate for the Pro Football Hall of Fame's class of 2026. Craig played 11 ...

The San Francisco 49ers lost who ESPN's Dan Graziano referred to as "the heart and soul of their defense" when linebacker Fred Warner went down with a dislocated and broken ankle in the 30-19 Week 6 ...