Low BAFF-receptor expression on B cells exiting the bone marrow may contribute to reduced peripheral B-cell survival and maturation. We included 91 patients with AAV (median age 60.78 years, IQR 51.14 ...

Your body is made of cells -- trillions of them. Cells are the basic building blocks of people and all other living things. Researchers study them to learn more about health and diseases.

You, me, and all of the 108 billion or so Homo sapiens who’ve ever walked the Earth have all been our own constellation of some 30 trillion cells. Each of our bodies is a collective organism of ...

As the researchers demonstrate, dendritic cells that are marked by expression of the transcription factor RORγt—so-called RORγt + dendritic cells (DCs)—are found in many tissues. Moreover ...

As part of the innate immune system, dendritic cells are in the body's first line of defense against infections. They detect pathogens and coordinate the immune response. An international team led ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

It's made up of a complicated network of cells and organs. It protects the body from infection, cancer, and other conditions. Lymph nodes are part of the immune system. They send out lymphocytes.

Therefore, we hypothesized that inhibition of DAI could prevent DCs from maturation and prolong murine allograft survival. Methods: Donor mouse bone marrow-derived dendritic cells (BMDCs) were ...