If you've been feeling weary, overwhelmed, or disconnected, your nervous system may not be asking for more effort. It may be ...

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for ...

Managing complement 3 glomerulopathy involves several treatment options aimed at slowing disease progression and protecting kidney function. These may include blood pressure control, steroids, ...

C3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare kidney conditions caused by an overactive complement system, part of the immune system. C3G ...

Also called C3G, this rare kidney disease often affects children and young adults, but it can happen at any age. It has a major impact on a person’s health and life. C3G has two forms: dense deposit ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

The complement system protects against infection, positively responds to tissue damage, clears cell debris, directs and modulates the adaptive immune system, and functions in neuronal development, ...

The complement system was first identified in the late nineteenth century as a heat-labile component of serum that ‘complements’ the antimicrobial activity of antibodies. Since then, it has become ...

Complement 3 glomerulopathy (C3 glomerulopathy) is a very rare kidney disease. Those diagnosed with it have one of two forms of this disease: dense deposit disease (DDD) or C3 glomerulonephritis (C3GN ...

The kidneys play a vital role in keeping us healthy, and it is often only when something goes wrong that we realize just how important they are. 1 Unfortunately, as many as 1 in 10 people are affected ...

Human C-reactive protein (CRP) activates the complement system to protect us from infections, but can also contribute toward progression of cardiovascular and autoimmune diseases when misactivated.

These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. Disruption of the complement system appears to precede the onset of islet autoimmunity (IA), making ...