How to Safely Taper Prednisone The risk of prednisone withdrawal is so high that some healthcare providers will pre-plan a tapering schedule if high doses are used for more than three days. In most ...

Tapering guidance is often specific to each person and may be based on age and body weight. However, a typical tapering regimen for an adult might require you to reduce your prednisone doses every ...

From baseline to week 52, reductions in the proportion of patients with active manifestations in the avacopan vs prednisone taper groups were 97.3% vs 96.5% (general), 100% vs 93.5% (nervous ...

When you take prednisone for more than a few weeks, your adrenal glands make way less cortisol. If you stop prednisone or taper too quickly, your body won’t have enough of the steroid it needs.

Prednisone contains synthetic cortisol. Using it can cause the body to stop making enough cortisol. Learn how to manage withdrawal symptoms when stopping this drug here.

At 52 weeks, avacopan plus rituximab is associated with a higher remission rate and improved recovery of renal function compared with prednisone taper plus rituximab, according to findings from a ...

A 52-week regimen of tocilizumab combined with an 8-week prednisone taper achieved sustained remission among a majority of patients with giant cell arteritis (GCA), suggesting potential efficacy for ...

Results from a pilot study examining a shortened prednisone taper of 8 weeks’ length rather than 26 weeks suggest it may be possible to reduce patients' duration of exposure to glucocorticoids.

More information: Robert F. Spiera et al, Sarilumab for Relapse of Polymyalgia Rheumatica during Glucocorticoid Taper, New England Journal of Medicine (2023). DOI: 10.1056/NEJMoa2303452 ...

Tapering doses of prednisone were administered in a blinded fashion at an initial dose of 15 mg per day for 2 weeks in the two groups to ensure adequate disease control at baseline (Table S1 in ...