Thorax

Journal club

Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are a significant cause of morbidity and ...
Thorax

Metered cryospray in patients with chronic bronchitis: a mechanistic randomised controlled study

Introduction Patients with chronic bronchitis suffer high morbidity and rapid functional decline; thus, novel treatments are ...
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Mobile instant messaging supported brief physical exercise intervention for smoking cessation: a community-based, cluster randomised controlled trial

Introduction Physical exercise has been used to assist smoking cessation, but supervised programmes are bounded by limited ...
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Socioeconomic deprivation and the outcome of pulmonary rehabilitation in England and Wales

6 Imperial College NHS Trust and NHLI, Imperial College, London, UK Background Pulmonary rehabilitation (PR) improves exercise capacity and health status in patients with COPD, but many patients ...
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Nationwide public health surveillance systems for asthma prevention and control: no data, no (health) gain!

Surveillance systems at the population level are of crucial importance to track diseases and detect trends over time. Among other benefits, these tools allow us to understand the distribution of ...
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Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis

Background Bronchiolisation of distal airspaces is an unexplained feature of idiopathic pulmonary fibrosis (IPF). The authors sought to identify mechanisms driving the differentiation of mucus cells ...
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Nasal high flow oxygen therapy in patients with COPD reduces respiratory rate and tissue carbon dioxide while increasing tidal and end-expiratory lung volumes: a randomised ...

Correspondence to Amanda Corley, Critical Care Research Group, Level 5 CSB, The Prince Charles Hospital, Rode Rd, Chermside, Brisbane, QLD 4032, Australia; amanda.corley{at}health.qld.gov.au The ...
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Non-invasive ventilation in acute respiratory failure

S Baudouin, S Blumenthal, B Cooper, C Davidson, A Davison, M Elliot, W Kinnear (Chairman), R Paton, E Sawicka, L Turner (Secretary) Non-invasive ventilation (NIV) refers to the provision of ...
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Pulmonary rehabilitation following hospitalisation for acute exacerbation of COPD: referrals, uptake and adherence

Rationale Several randomised controlled trials support the provision of early pulmonary rehabilitation (PR) following hospitalisation for acute exacerbation of chronic obstructive pulmonary disease ...
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A morphometric study of mucins and small airway plugging in cystic fibrosis

1 Service de Pneumologie and UPRES EA 2511, Université René Descartes, Hôpital Cochin, AP-HP, Paris, France 2 Laboratoire d’Anatomie Pathologique, Hôpital Européen Georges Pompidou, AP-HP, Paris, ...
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Different responses of the oral, nasal and lung microbiomes to cigarette smoke

1 Technical University of Munich ZIEL - Institute for Food and Health, Freising, Germany 6 German Center for Lung Research (DZL), Airway Research Center North (ARCN), Borstel, Germany To examine the ...
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Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study

Background: The rising prevalence of asthma in developed nations may be associated with the rising prevalence of obesity in these same nations. The relationship between body mass index (BMI) and the ...