Bendamustine Explained in 3 Minutes 💉 | Mechanism of Action, Uses, Dosage, Dilution & Side Effects
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Bendamustine is a unique chemotherapeutic agent with several distinct pharmacological characteristics. It is a nitrogen mustard that combines both alkylating and antimetabolite properties. As an Alkylating agent, It crosslinks DNA strands leading to DNA breakage and inhibition of DNA synthesis and function, resulting in cancer cell death. Its antimetabolite action is due to its benzimidazole ring, which resembles purine bases, interfering with DNA replication and repair. #medicine #cancer #oncol
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