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New NIH-funded brain tumor research led by @UCSF neurosurgery resident Alex Haddad, MD, and neurosurgeon Manish Aghi, MD, PhD, developed a novel viral immunotherapy for glioblastoma. The innovative approach uses a replicating retrovirus to turn the tumor cells into biofactories that produce an immune-stimulating cytokine called receptor-linked IL-15, generating a durable anti-tumor response. Read the full study at the link in our bio. #ScienceTok #glioblastoma #immunotherapy
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“We Probably Shouldn’t Play With Viruses” #wait Glioblastoma multiforme (GBM) is one of the most aggressive and deadly forms of brain cancer, often resistant to traditional treatments like surgery, chemotherapy, and radiation. Its fast growth, ability to spread quickly within the brain, and high recurrence rate make GBM one of humanity’s worst enemies in the fight against cancer. Most patients face a poor prognosis, with survival often measured in months rather than years, and the complex nature
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Unfortunately glioblastoma, the most aggressive form of brain cancer, is becoming increasingly common. In the U.S., it accounts for nearly 50% of all malignant brain tumors, and its incidence has been rising by about 1.4% per year in adults over age 65. Glioblastoma develops from glial cells, specifically astrocytes, which normally provide structural and metabolic support to neurons. It is known for its quick progression, resistance to treatment, and poor prognosis. Part of the reason why gliobl
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Glioblastoma is one of the most aggressive brain tumors known to medicine — and the biology behind why makes it especially devastating. 🧠 Neurons and mature muscle fibers don't typically divide, which is why they rarely form tumors. But glial cells do divide — and when they accumulate enough DNA mutations, that division can spiral out of control. The result is a glioblastoma, most commonly arising from astrocytes. Unlike meningiomas that grow on the outside of the brain and compress inward, gli
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